Vario may refer to:
- Paul Vario (1914–1988), high-ranking member of the Lucchese crime family
- João Vário (1937–2007), Cape Verdean writer, neurosurgeon, scientist, and professor
- Akhtar Ali Vario (died 2008), politician
- MDA Vario, a version of the HTC Wizard smartphone
- Vario (Pokémon), a Pokémon Colosseum character
- Variometer, an aircraft flight instrument sometimes shortened to "vario"